The A4 study: Now is the time to join the fight to prevent Alzheimer's disease.

Association of sleep and beta-amyloid pathology among older cognitively unimpaired adults

Insel PS, Mohlenhoff BS, Neylan TC, Krystal AD, Mackin RS. JAMA network open; JAMA Netw Open. 2021;4(7):e2117573.
READ MORE

Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study

Sato K, Ihara R, Suzuki K, et al. Alzheimer’s & dementia : translational research & clinical interventions; Alzheimers Dement (N Y). 2021;7(1):e12135-n/a.
READ MORE

Gene- and age-informed screening for preclinical Alzheimer’s disease trials

Spencer BE, Digma LA, Jennings RG, Brewer JB. Alzheimers Dement. 2021;17(3):457-465.
READ MORE

KL*VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE* 4 carriers

Belloy, M. E., Eger, S. J., Le Guen, Y., Napolioni, V., Deters, K. D., Yang, H. S., … & Alzheimer’s Disease Neuroimaging Initiative. Neurobiol Aging. 2021 May; 101: 123–129.
READ MORE

Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study

Marshall, G. A., Sikkes, S. A., Amariglio, R. E., Gatchel, J. R., Rentz, D. M., Johnson, K. A., … & Full listing of A4 Study team and site personnel available at A4STUDY. org. Alzheimers Dement (Amst). 2020; 12(1): e12118.
READ MORE

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

Dumitrescu, L., Mahoney, E. R., Mukherjee, S., Lee, M. L., Bush, W. S., Engelman, C. D., … & Hohman, T. J. Brain. 2020 Aug; 143(8): 2561–2575.
READ MORE

Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment

Grill, J. D., Raman, R., Ernstrom, K., Sultzer, D. L., Burns, J. M., Donohue, M. C., … & A4 Study Team. JAMA Neurol. 2020 Dec; 77(12): 1–10.
READ MORE

The Computerized Cognitive Composite (C3) in A4, an Alzheimer’s Disease Secondary Prevention Trial

Papp, K. V., Rentz, D. M., Maruff, P., Sun, C. K., Raman, R., Donohue, M. C., … & Sperling, R. A. J Prev Alzheimers Dis. 2021; 8(1): 59–67.
READ MORE

Your upload was successful!