First A4 Screening Data Paper Published
National Institute on Aging READ MORE
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Journal Articles Featuring A4 Data
Depression screening in cognitively normal older adults: Measurement bias according to subjective memory decline, brain amyloid burden, cognitive function, and sex
Thompson, L. I., & Jones, R. N. (2020). Depression screening in cognitively normal older adults: Measurement bias according to subjective memory decline, brain amyloid burden, cognitive function, and sex. Alzheimer’s & dementia (Amsterdam, Netherlands), 12(1), e12107. ht READ MORE
Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants
Harkins, K., Sankar, P., Sperling, R., Grill, J. D., Green, R. C., Johnson, K. A., … & Karlawish, J. (2015). Development of a process to disclose amyloid imaging results to cognitively normal older adult research participants. Alzheimer’s research & therapy, 7(1), 1-9. READ MORE
KL* VS Heterozygosity Reduces Brain Amyloid in Asymptomatic at Risk APOE* 4 Carriers.
Belloy, M. E., Eger, S. J., Le Guen, Y., Napolioni, V., Deters, K. D., Yang, H. S., … & Alzheimer’s Disease Neuroimaging Initiative. (2021). KL* VS Heterozygosity Reduces Brain Amyloid in Asymptomatic at Risk APOE* 4 Carriers. Neurobiology of Aging. READ MORE
Genetic variants and functional pathways associated with resilience to Alzheimer’s disease
Dumitrescu, L., Mahoney, E. R., Mukherjee, S., Lee, M. L., Bush, W. S., Engelman, C. D., … & Hohman, T. J. (2020). Genetic variants and functional pathways associated with resilience to Alzheimer’s disease. Brain, 143(8), 2561-2575. READ MORE
Short-term psychological outcomes of disclosing amyloid imaging results to research participants who do not have cognitive impairment
Grill, J. D., Raman, R., Ernstrom, K., Sultzer, D. L., Burns, J. M., Donohue, M. C., … & A4 Study Team. (2020). Short-term psychological outcomes of disclosing amyloid imaging results to research participants who do not have cognitive impairment. JAMA neurology, 77(12), 1504-1513. READ MORE
Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals
Sperling, R. A., Donohue, M. C., Raman, R., Sun, C. K., Yaari, R., Holdridge, K., … & Aisen, P. S. (2020). Association of factors with elevated amyloid burden in clinically normal older individuals. JAMA neurology, 77(6), 735-745. READ MORE
The computerized cognitive composite (c3) in a4, an alzheimer’s disease secondary prevention trial.
Papp, K. V., Rentz, D. M., Maruff, P., Sun, C. K., Raman, R., Donohue, M. C., … & Sperling, R. A. (2020). The computerized cognitive composite (c3) in a4, an alzheimer’s disease secondary prevention trial. The journal of prevention of Alzheimer’s disease, 1-9. READ MORE
Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study.
Marshall, G. A., Sikkes, S. A., Amariglio, R. E., Gatchel, J. R., Rentz, D. M., Johnson, K. A., … & Full listing of A4 Study team and site personnel available at A4STUDY. org. (2020). Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adult READ MORE
The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults
Insel, P. S., Donohue, M. C., Sperling, R., Hansson, O., & Mattsson‐Carlgren, N. (2020). The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults. Annals of clinical and translational neurology, 7(5), 776-785. READ MORE
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